Shri Eknath Khadse is known for his profound interest in social, cultural and educational work ,as much as his political work. He has continued to work as Senate Member of Pune University from 1990 and also as Member of the Managing Committee, Mahatma Phule Agriculture University, Rahuri, from 2002 till today.
While working as Minister for Higher and Technical Education, he established one ITI in every tehsil of the state and thus established 358 ITI's across the state. He also took important progressive decisions of reserving 30% seats for girls in these ITI's and also the decision of keeping 2% seats reserved for Hindu refugees of Kashmir. He forced these governments to reserve 10% cots for BPL beneficiaries in the trust hospitals.
He also kept constant pressure on the government to implement reservations at every step during the promotion of OBC employees and officers.
Hundreds of beneficiaries took advantage of "Jivandayi Arogya Yojana" and CM relief fund for heart surgeries, kidney disease, cancer and brain disease through his efforts. As a minister of Irrigation of Maharashtra for 2 years, he has approved many irrigation projects, completed many incomplete projects and beyond that completed many irrigation boosting projects under Krishna Valley Development Corporation.
Rehabilitation first, then irrigation – was his slogan when he was irrigation minister of Maharashtra.
Formed North Maharashtra Tapi valley Development Corporation. Under this completed work worth five thousand crore. He finished the backlog of irrigation projects just in two years of him being irrigation minister.